Catalog No.: PC-23736Not For Human Use, Lab Use Only.
USP30-I-1 (USP30-IN-1) is a potent, selective and covalent inhibitor of mitochondrial deubiquitinating (DUB) enzyme USP30 with IC50 of 94 nM, shows no significant activity against other 40 endogenous DUBs.
USP30-I-1 (USP30-IN-1) is a potent, selective and covalent inhibitor of mitochondrial deubiquitinating (DUB) enzyme USP30 with IC50 of 94 nM, shows no significant activity against other 40 endogenous DUBs.
USP30-I-1 is a selective and potent inhibitor of USP30 at concentrations ≤1 µM.
USP30-I-1 inhibited USP30 in a dose-dependent manner, with an IC50 of 4 nM in fluorescence intensity measurements.
USP30-I-1 binds to the catalytic cysteine (Cys77) of USP30.
