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Chemical Structure : USP30 inhibitor Q14 peptide
Catalog No.: PC-72255Not For Human Use, Lab Use Only.
USP30 inhibitor Q14 peptide is a potent peptide inhibitor of USP30 with IC50 of 57.2 nM, inhibits the deubiquitinating activities of USP30, increases mitophagy.
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USP30 inhibitor Q14 peptide is a potent peptide inhibitor of USP30 with IC50 of 57.2 nM, inhibits the deubiquitinating activities of USP30, increases mitophagy.
Q14 peptide (18 aa) is derived from the transmembrane (TM) domain of USP30 that can target mitochondrial-anchored USP30 directly and increase mitophagy.
Q14 peptide inhibits the deubiquitinating activities of USP30 on both purified ubiquitin chains and ubiquitinated mitochondria.
Q14 peptide binds USP30 in vitro with Kd of 37 nM in fluorescence polarization (FP) assays.
| M.Wt | 2157.60 | |
| Formula | C99H165N31O23 | |
| Appearance | Solid | |
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1. Xuan Qin, et al. Autophagy. 2022 Jan 6;1-20.
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