Chemical Structure : USP5 inhibitor 64
CAS No.: 2851040-81-6
Catalog No.: PC-72414Not For Human Use, Lab Use Only.
USP5 inhibitor 64 is a selective chemical probe (inhibitor) against USP5 deubiquitinase, binds to the USP5 ZnF-UBD (zinc-finger ubiquitin binding domain) with KD of 2.8 uM.
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USP5 inhibitor 64 is a selective chemical probe (inhibitor) against USP5 deubiquitinase, binds to the USP5 ZnF-UBD (zinc-finger ubiquitin binding domain) with KD of 2.8 uM.
USP5 inhibitor 64 is selective over nine proteins containing structurally similar ZnF-UBD domains.
USP5 inhibitor 64 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate in an in vitro assay.
M.Wt | 437.895 | |
Formula | C19H20ClN3O5S | |
Appearance | Solid | |
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Chemical Name/SMILES |
(5-((4-(4-chlorophenyl)piperidin-1-yl)sulfonyl)picolinoyl)glycine |
1. Mandeep K Mann, et al. J Med Chem. 2021 Oct 28;64(20):15017-15036.
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