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Chemical Structure : USP7-797
Catalog No.: PC-38191Not For Human Use, Lab Use Only.
USP7-797 (RAPT41) is a novel potent selective inhibitor of USP7 with IC50 of 0.44 nM.
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USP7-797 (RAPT41) is a novel potent selective inhibitor of USP7 with IC50 of 0.44 nM.
USP7-797 (RAPT41) inhibits the growth of p53-mutant small cell lung cancer cell line H526 at a CC50 of 450 nM.
USP7-797 (RAPT41) demonstrates tumor growth inhibition in both p53 wildtype and p53 mutant cancers.
| M.Wt | 510.049 | |
| Formula | C27H28ClN3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yamini M Ohol, et al. Mol Cancer Ther. 2020 Oct;19(10):1970-1980.
2. Paul R Leger, et al. J Med Chem. 2020 May 28;63(10):5398-5420.
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