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UU-T01

Chemical Structure : UU-T01

CAS No.: 1417162-83-4

UU-T01 (UU-T 01)

Catalog No.: PC-61799Not For Human Use, Lab Use Only.

UU-T01 is a novel small-molecule inhibitor of β-catenin/Tcf4 protein-protein interaction with Ki of 3.14 uM, binds to β-catenin with Kd of 0.531 uM..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    UU-T01 is a novel small-molecule inhibitor of β-catenin/Tcf4 protein-protein interaction with Ki of 3.14 uM, binds to β-catenin with Kd of 0.531 uM.

    Physicochemical Properties

    M.Wt 230.231
    Formula C10H10N6O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-(2-(2H-tetrazol-5-yl)ethyl)-1H-indazol-1-ol

    References

    1. Yu B, et al. ACS Chem Biol. 2013 Mar 15;8(3):524-9.

    2. Yan M, et al. Exp Biol Med (Maywood). 2017 Jun;242(11):1185-1197.

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