UU-T02 |CAS:1500080-17-0 Probechem Biochemicals

Chemical Structure : UU-T02

UU-T02 (UU-T 02)

Catalog No.: PC-61800Not For Human Use, Lab Use Only.

UU-T02 is a novel potent, selective small-molecule inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM.

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Biological Activity

UU-T02 is a novel potent, selective small-molecule inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM.
UU-T02 displays 63-fold and 175-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions, respectively.

Physicochemical Properties

M.Wt	665.096
Formula	C33H33ClN4O9
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-((S)-3-carboxy-2-((S)-2-(2-(5-chloro-1H-indol-2-yl)acetamido)-3-(naphthalen-2-yl)propanamido)propanamido)-5-methoxy-5-oxopentanoic acid

References

1. Huang Z, et al. ACS Chem Biol. 2014 Jan 17;9(1):193-201.

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UU-T02 (UU-T 02)

Biological Activity

Physicochemical Properties

References

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