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Chemical Structure : UU-T03
Catalog No.: PC-61801Not For Human Use, Lab Use Only.
UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM.
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UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM。
UU-T03 exhibits growth inhibition of SW480 cells with IC50 of 10.77 uM。
UU-T03 downregulates the transcription of AXIN2, LGR5, cyclin D1, and c-Myc in dose-dependent manners in SW480 cells.
| M.Wt | 721.204 | |
| Formula | C37H41ClN4O9 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Huang Z, et al. ACS Chem Biol. 2014 Jan 17;9(1):193-201.
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