Chemical Structure : UVI 2008
Catalog No.: PC-70296Not For Human Use, Lab Use Only.
UVI 2008 is a RARβ/γ agonist originated from TTNPB, is also a selective inhibitor of aldo-keto reductase family member 1B10 (AKR1B10) with IC50 of 6.1 uM.
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UVI 2008 is a RARβ/γ agonist originated from TTNPB, is also a selective inhibitor of aldo-keto reductase family member 1B10 (AKR1B10) with IC50 of 6.1 uM.
UVI 2008 shows >10-fold selectivity over the closely related aldose reductase (AR, IC50=70 uM).
M.Wt | 427.382 | |
Formula | C24H27BrO2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Ruiz FX, et al. Chem Biol Interact. 2017 Feb 1. pii: S0009-2797(17)30109-6.
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