Chemical Structure : UVI3003
CAS No.: 847239-17-2
Catalog No.: PC-70298Not For Human Use, Lab Use Only.
UVI3003 (UVI 3003) is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity, inhibits xenopus and human RXRα in Cos7 cells with IC50 of 0.22 and 0.24 uM, respectively.
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| 10 mg | $128 | In stock | |
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| 50 mg | $358 | In stock | |
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UVI3003 (UVI 3003) is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity, inhibits xenopus and human RXRα in Cos7 cells with IC50 of 0.22 and 0.24 uM, respectively.
UVI 3003 does not affect the corepressor interaction capacity of the RARα subunit in the RAR-RXR heterodimer configuration.
| M.Wt | 436.6 | |
| Formula | C28H36O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-[4-hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoic acid |
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1. Habchi J, et al. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E200-E208.
2. Nahoum V, et al. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8.

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