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Chemical Structure : Up284
Catalog No.: PC-22711Not For Human Use, Lab Use Only.
Up284 is a small molecule inhibitor of proteasome's 19S Regulatory Particle (RP) ubiquitin receptor RPN13 (ADRM1, hRPN13, or GP110), covalently binds RPN13 and induces rapid apoptosis in ovarian cancer cells.
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Up284 is a small molecule inhibitor of proteasome's 19S Regulatory Particle (RP) ubiquitin receptor RPN13 (ADRM1, hRPN13, or GP110), covalently binds RPN13 and induces rapid apoptosis in ovarian cancer cells.
| M.Wt | 365.44 | |
| Formula | C24H19N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Anchoori RK, et al. PLoS One. 2023 Jun 14;18(6):e0285221.
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