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Upacicalcet

Chemical Structure : Upacicalcet

CAS No.: 1333218-50-0

Upacicalcet

Catalog No.: PC-61402Not For Human Use, Lab Use Only.

Upacicalcet is a novel positive allosteric modulator of the calcium-sensing receptor (CaSR), a novel secondary hyperparathyroidism drug that targets the amino acid binding site of CaSR.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Upacicalcet is a novel positive allosteric modulator of the calcium-sensing receptor (CaSR), a novel secondary hyperparathyroidism drug that targets the amino acid binding site of CaSR.

Physicochemical Properties

M.Wt 351.758
Formula C11H14ClN3O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S)-2-amino-3-{[(3-chloro-2-methyl-5-sulfophenyl)carbamoyl]amino}propanoic acid

References

1, Sato H, et al. Mol Pharmacol. 2022 Oct;102(4):183-195.
2, Sato H, et al. Bone. 2023 Feb;167:116613.

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