Chemical Structure : VAS3947
CAS No.:
869853-70-3
VAS3947
(VAS-3947, VAS 3947)
Catalog No. : PC-27684Not For Human Use, Lab Use Only.
VAS3947 is a specific pan-NADPH oxidase (NOX) inhibitor with IC50 of 86.8, 5.6, 30.5 and 39.2 uM for NOX1, 2, 4 and 5 respectively.
Packing Price Stock Quantity 5 mg $78 In stock 0 1 2 3 4 5 10 mg $118 In stock 0 1 2 3 4 5 25 mg $198 In stock 0 1 2 3 4 5 50 mg Get quote 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2768401
Biological Activity
VAS3947 is a specific pan-NADPH oxidase (NOX) inhibitor with IC50 of 86.8, 5.6, 30.5 and 39.2 uM for NOX1, 2, 4 and 5 respectively.
Physicochemical Properties
M.Wt
310.34
Formula
C14H10N6OS
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-((3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)oxazole
References
1. Lu WJ, et al. Sci Rep. 2019 Dec 11;9(1):18852.
2. Wind S, et al. Br J Pharmacol. 2010 Oct;161(4):885-98.
3. Hecht N, et al. Eur J Pharm Biopharm. 2017 Jun;115:206-217.
4. Joana Reis, et al. Redox Biol. 2020 May:32:101466.
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