VH032 | VHL ligand | Probechem Biochemicals

Chemical Structure : VH032

CAS No.: 1448188-62-2

Catalog No.: PC-60116Not For Human Use, Lab Use Only.

VH032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM.

Packing	Price	Stock
10 mg	$138	In stock
25 mg	$218	In stock
50 mg	$358	In stock
100 mg	$558	In stock
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Biological Activity

VH032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM.

M.Wt	472.604
Formula	C24H32N4O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,4R)-1-((S)-2-acetamido-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

1. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.

2. Galdeano C, et al. J Med Chem. 2014 Oct 23;57(20):8657-63.