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VHL Ligand 3 (VH032-Boc)

Chemical Structure : VHL Ligand 3 (VH032-Boc)

CAS No.: 1448189-98-7

VHL Ligand 3 (VH032-Boc) ((S,R,S)-AHPC-Boc)

Catalog No.: PC-60115Not For Human Use, Lab Use Only.

(S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein and PROTAC technology.

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500 mg $398 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

(S,R,S)-AHPC-Boc (VH032-Boc) is a ligand used in the recruitment of the von Hippel-Lindau (VHL) protein and PROTAC technology.

Physicochemical Properties

M.Wt 530.684
Formula C27H38N4O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

tert-butyl ((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate

References

1. Wurz RP, et al. J Med Chem. 2017 Apr 17. doi: 10.1021/acs.jmedchem.6b01781.

2. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.

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