VT204 | KRAS G12C inhibitor | Probechem Biochemicals

Chemical Structure : VT204

Catalog No.: PC-22825Not For Human Use, Lab Use Only.

VT204 is a small molecule inhibitor of KRAS G12C, effectively suppresses cell proliferation in NCI-H358 cells at 8 uM.

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Biological Activity

VT204 is a small molecule inhibitor of KRAS G12C, effectively suppresses cell proliferation in NCI-H358 cells at 8 uM.

M.Wt	514.98
Formula	C24H21ClF2N6OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-((2R,5S)-4-(7-(2-amino-7-fluorobenzo[d]thiazol-4-yl)-6-chloro-8-fluoroquinazolin-4-yl)-2,5-dimethylpiperazin-1-yl)prop-2-en-1-one

1. Xuechao Yang, et al. Technol Cancer Res Treat. 2024 Jan-Dec:23:15330338241264853.