Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : VTI-1002
Catalog No.: PC-35175Not For Human Use, Lab Use Only.
VTI-1002 is a first-in-class, highly potent, selective inhibitor of human Granzyme B (GzmB) with Ki of 4.4 nM, exhibits strong selectivity for GzmB over caspases 3-10, cathepsin G, and neutrophil elastase.
| Packing | Price | Stock | Quantity |
|---|
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
VTI-1002 is a first-in-class, highly potent, selective inhibitor of human Granzyme B (GzmB) with Ki of 4.4 nM, exhibits strong selectivity for GzmB over caspases 3-10, cathepsin G, and neutrophil elastase.
VTI-1002 is nearly 20 times more potent against human GzmB than Ac-IEPD-CHO (Ki=80 nM), exhibits potent inhibition against mouse GzmB (IC50=179 nM).
VTI-1002 improves remodeling in a murine model of impaired burn wound healing.
| M.Wt | ||
| Formula | ||
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
