VU0092273

Chemical Structure : VU0092273

Catalog No.: PC-22907Not For Human Use, Lab Use Only.

VU0092273 is a potent mGlu5 positive allosteric modulator (PAM) with an EC50 of 0.27 uM, binds to the MPEP site.

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Biological Activity

VU0092273 is a potent mGlu5 positive allosteric modulator (PAM) with an EC50 of 0.27 uM, binds to the MPEP site.

M.Wt	305.38
Formula	C20H19NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4-hydroxypiperidin-1-yl)(4-(phenylethynyl)phenyl)methanone

1. Rodriguez AL, et al. Mol Pharmacol. 2010 Dec;78(6):1105-23.