Chemical Structure : VU0155069
CAS No.:
1130067-06-9
VU0155069
(VU 0155069, CAY10593)
Catalog No. : PC-63190Not For Human Use, Lab Use Only.
VU0155069 is a potent, selective phospholipase D1 (PLD1) inhibitor with IC50 of 46 nM, 20-fold selectivity over PLD2 (IC50=933 nM).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6319001
Biological Activity
VU0155069 (CAY10593) is a potent, selective phospholipase D1 (PLD1 ) inhibitor with IC50 of 46 nM, 20-fold selectivity over PLD2 (IC50=933 nM).
Physicochemical Properties
M.Wt
462.978
Formula
C26H27ClN4O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
N-[(1S)-2-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl]-2-naphthalenecarboxamide
References
1. Scott SA, et al. Nat Chem Biol.
2. Song HI, et al. Sci Rep.
3. Kang DW, et al. Clin Cancer Res.
4. Cheng M, et al. Neoplasia.
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