Chemical Structure : VU0155094
Catalog No.: PC-62130Not For Human Use, Lab Use Only.
VU0155094 (ML397) is a potent, selective pan-Group III mGlu positive allosteric modulator with IC50 of 3.43/1.5/0.93 uM for mGlu8/7/4, respectively.
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VU0155094 (ML397) is a potent, selective pan-Group III mGlu positive allosteric modulator with IC50 of 3.43/1.5/0.93 uM for mGlu8/7/4, respectively.
VU0155094 displays >30-fold selectivity over groups I and II mGlus (mGlu1/2/3/5/6).
M.Wt | 436.526 | |
Formula | C24H24N2O4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Jalan-Sakrikar N, et al. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37.
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