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Chemical Structure : VU0364770
CAS No.: 61350-00-3
Catalog No.: PC-42205Not For Human Use, Lab Use Only.
VU0364770 is a potent, selective, systemically active positive allosteric modulator of mGlu4R with EC50 of 1.1 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $298 | In stock | |
| 250 mg | Get quote |
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VU0364770 is a potent, selective, systemically active positive allosteric modulator of mGlu4R with EC50 of 1.1 uM.
VU0364770 does not significantly bind to a panel of 68 GPCRs, ion channels and transporters.
VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease.
| M.Wt | 232.6657 | |
| Formula | C12H9ClN2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-Pyridinecarboxamide, N-(3-chlorophenyl)- |
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1. Jones CK, et al. J Pharmacol Exp Ther. 2012 Feb;340(2):404-21.
2. Iderberg H, et al. Neuropharmacology. 2015 Aug;95:121-9.
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