Chemical Structure : VU0486321
Catalog No.: PC-23779Not For Human Use, Lab Use Only.
VU0486321 is a potent, selective metabotropic glutamate receptor subtype 1 (mGlu1, mGluR1) positive allosteric modulator (PAM) with EC50 of 31.87 nM (human Glu1), 35-fold selective over mGlu4.
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VU0486321 is a potent, selective metabotropic glutamate receptor subtype 1 (mGlu1, mGluR1) positive allosteric modulator (PAM) with EC50 of 31.87 nM (human Glu1), 35-fold selective over mGlu4.
M.Wt | 398.77 | |
Formula | C20H12ClFN2O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Garcia-Barrantes PM, et al. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5107-10.
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