VU6001192 | mGlu2 NAM | Probechem Biochemicals

Chemical Structure : VU6001192

VU6001192 (VU-6001192)

Catalog No.: PC-27119Not For Human Use, Lab Use Only.

VU6001192 is a potent and highly selective mGlu2 negative allosteric modulator (NAM) with IC50 of 207 nM in calcium mobilization mGlu2 assays, is inactive against mGlu3 up to 30 uM

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Biological Activity

VU6001192 is a potent and highly selective mGlu2 negative allosteric modulator (NAM) with IC50 of 207 nM in calcium mobilization mGlu2 assays, is inactive against mGlu3 up to 30 uM

Physicochemical Properties

M.Wt	409.46
Formula	C23H24FN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(((2S,6R)-2,6-dimethylmorpholino)methyl)-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

References

1. Felts AS, et al. J Med Chem. 2015 Nov 25;58(22):9027-40.

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VU6001192 (VU-6001192)

Biological Activity

Physicochemical Properties

References

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