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Chemical Structure : VU 6001966
Catalog No.: PC-60939Not For Human Use, Lab Use Only.
VU 6001966 is a potent and selective, CNS penetrant mGlu2 negative allosteric modulator with IC50 of 78 nM.
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VU 6001966 is a potent and selective, CNS penetrant mGlu2 negative allosteric modulator with IC50 of 78 nM.
VU 6001966 shows no inhibition for mGlu3 (IC50>30 uM).
VU 6001966 represents an exciting lead series for potential mGlu2 PET tracer development.
| M.Wt | 326.331 | |
| Formula | C17H15FN4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bollinger KA, et al. ACS Med Chem Lett. 2017 Aug 3;8(9):919-924.
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