Catalog No.: PC-23781Not For Human Use, Lab Use Only.
VU6004909 is a selective, CNS penetrant metabotropic glutamate receptor subtype 1 (mGlu1) positive allosteric modulator (PAM) with EC50 of 25.7 nM and 31 nM for human and rat mGlu1 respectively.
VU6004909 is a selective, CNS penetrant metabotropic glutamate receptor subtype 1 (mGlu1) positive allosteric modulator (PAM) with EC50 of 25.7 nM and 31 nM for human and rat mGlu1 respectively. VU6004909 reduces dorsolateral striatal dopamine (DA) release in vivo and displays antipsychotic efficacy.
