Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-mGluR-VU6010608
VU6010608

Chemical Structure : VU6010608

CAS No.: 2165325-42-6

Add to Favorites

VU6010608 (VU 6010608;VU-6010608)

Catalog No.: PC-60149Not For Human Use, Lab Use Only.

VU6010608 is a potent, highly selective, CNS penetrant mGlu7 negative allosteric modulator with IC50 of 0.76 uM.

Packing Price Stock Quantity
10 mg Get quote
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    VU6010608 is a potent, highly selective, CNS penetrant mGlu7 negative allosteric modulator with IC50 of 0.76 uM.
    VU6010608 shows no activity against mGlu1,2,3,4,5,6,8, as well as a penel of 68 GPCRs, ion channels and transporters (IC50>10 uM).
    VU6010608 blocks long-term potentiation (LTP) at SC-CA1 synapses in mice brain slices induced by high frequency stimulation.

    Physicochemical Properties

    M.Wt 408.337
    Formula C18H15F3N4O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-3,4-dimethoxybenzamide

    References

    1. Carson W. Reed, et al. ACS Med. Chem. Lett., 2017, 8 (12), pp 1326-1330.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: