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VU6024945

Chemical Structure : VU6024945

CAS No.: 3107596-97-1

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VU6024945 (VU-6024945)

Catalog No.: PC-27668Not For Human Use, Lab Use Only.

VU6024945 is a potent, selective mGlu5 negative allosteric modulator (NAM) with IC50 of 110 nM (hmGlu5).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VU6024945 is a potent, selective mGlu5 negative allosteric modulator (NAM) with IC50 of 110 nM (hmGlu5).

Physicochemical Properties

M.Wt 340.34
Formula C15H14F2N2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-2,3-difluoro-N-(4-methylthiazol-2-yl)-5-((tetrahydrofuran-3-yl)oxy)benzamide

References

1. Crocker KE, et al. ACS Med Chem Lett. 2025 Apr 22;16(5):865-874.

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