VU6031545

Chemical Structure : VU6031545

Catalog No.: PC-27663Not For Human Use, Lab Use Only.

VU6031545 is a potent, selective mGlu5 negative allosteric modulator (NAM) with IC50 of 22 nM (hmGlu5).

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Biological Activity

VU6031545 is a potent, selective mGlu5 negative allosteric modulator (NAM) with IC50 of 22 nM (hmGlu5).

M.Wt	361.43
Formula	C16H15N3O3S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-(4-Methylthiazol-2-yl)-7-((tetrahydrofuran-3-yl)oxy)thieno[3,2-b]pyridine-5-carboxamide

1. Crocker KE, et al. ACS Med Chem Lett. 2025 Apr 22;16(5):865-874.