VU6035386 | mGluR5 NAM | Probechem Biochemicals

Chemical Structure : VU6035386

Catalog No.: PC-26037Not For Human Use, Lab Use Only.

VU6035386 is a potent, selective negative allosteric modulator (NAM) of metabotropic glutamate receptor subtype 5 (mGlu5, mGluR5) with IC50 of 64 nM.

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Biological Activity

VU6035386 is a potent, selective negative allosteric modulator (NAM) of metabotropic glutamate receptor subtype 5 (mGlu5, mGluR5) with IC50 of 64 nM.

M.Wt	364.40
Formula	C19H13FN4OS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-Fluoropyridin-2-yl)-7-(4-methylpyridin-3-yl)thieno[3,2-b]pyridine-5-carboxamide

1. Henderson SH, et al. ACS Chem Neurosci. 2026 Feb 4;17(3):610-623.