VU6046980 | mGlu7 PAM | Probechem Biochemicals

Chemical Structure : VU6046980

Catalog No.: PC-49586Not For Human Use, Lab Use Only.

VU6046980 is a potent, selective and in vivo active mGlu7 positive allosteric modulator (PAM) with EC50 of 0.15 uM (rat mGlu7).

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Biological Activity

VU6046980 is a potent, selective and in vivo active mGlu7 positive allosteric modulator (PAM) with EC50 of 0.15 uM (rat mGlu7).

M.Wt	409.397
Formula	C21H17F2N5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-6-fluoro-4-(10-fluoro-1,2,4a,5-tetrahydrobenzo[b]pyrazino[1,2-d][1,4]oxazin-3(4H)-yl)-8-methoxycinnoline-3-carbonitrile

1. Jacob J Kalbfleisch, et al. Bioorg Med Chem Lett. 2022 Dec 15;80:129106