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VUF11222

Chemical Structure : VUF11222

CAS No.: 1414376-84-3

VUF11222 (VUF 11222)

Catalog No.: PC-21816Not For Human Use, Lab Use Only.

VUF11222 is a potent, selective and nonpeptidomimetic CXCR3 agonist with binding pKi of 7.2, and pEC50 of 6.1 in [35S]GTPγS functional assays.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VUF11222 is a potent, selective and nonpeptidomimetic CXCR3 agonist with binding pKi of 7.2, and pEC50 of 6.1 in [35S]GTPγS functional assays.

Physicochemical Properties

M.Wt 552.34
Formula C25H31BrIN
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(2'-Bromobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium Iodide

References

1. Wijtmans M, et al. J Med Chem. 2012 Dec 13;55(23):10572-83.

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