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Chemical Structure : VUF11418
CAS No.: 1414376-85-4
Catalog No.: PC-38487Not For Human Use, Lab Use Only.
VUF11418 is a selective, nonpeptidomimetic agonist of CXCR3 with binding pKi vaule of 7.2, pEC50 value of 6.0 in [35S]GTPγS functional assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $178 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 100 mg | Get quote | ||
| 1 g | Get quote |
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VUF11418 is a selective, nonpeptidomimetic agonist of CXCR3 with binding pKi vaule of 7.2, pEC50 value of 6.0 in [35S]GTPγS functional assays.
VUF11418 is a highly useful chemical tool for detailed assessment of CXCR3 activation as well as for studying downstream CXCR3 signaling.
| M.Wt | 599.339 | |
| Formula | C25H31I2N | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2'-Iodo-N-[[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methyl]-N,N-dimethyl-[1,1'-biphenyl]-4-methanaminium iodide |
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1. Wijtmans M, et al. J Med Chem. 2012 Dec 13;55(23):10572-83.
2. Scholten DJ, et al. Mol Pharmacol. 2015 Apr;87(4):639-48.
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