Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-GPCR-Chemokine Receptor (CCR and CXCR)-VUF11418
VUF11418

Chemical Structure : VUF11418

CAS No.: 1414376-85-4

Add to Favorites

VUF11418 (VUF 11418)

Catalog No.: PC-38487Not For Human Use, Lab Use Only.

VUF11418 is a selective, nonpeptidomimetic agonist of CXCR3 with binding pKi vaule of 7.2, pEC50 value of 6.0 in [35S]GTPγS functional assays.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

VUF11418 is a selective, nonpeptidomimetic agonist of CXCR3 with binding pKi vaule of 7.2, pEC50 value of 6.0 in [35S]GTPγS functional assays.
VUF11418 is a highly useful chemical tool for detailed assessment of CXCR3 activation as well as for studying downstream CXCR3 signaling.

Physicochemical Properties

M.Wt 599.339
Formula C25H31I2N
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2'-Iodo-N-[[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methyl]-N,N-dimethyl-[1,1'-biphenyl]-4-methanaminium iodide

References

1. Wijtmans M, et al. J Med Chem. 2012 Dec 13;55(23):10572-83.

2. Scholten DJ, et al. Mol Pharmacol. 2015 Apr;87(4):639-48.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: