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VUT-MK142

Chemical Structure : VUT-MK142

CAS No.: 1313491-22-3

VUT-MK142

Catalog No.: PC-63220Not For Human Use, Lab Use Only.

VUT-MK142 is a cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes, shows superior cardiomyogenic activity over cardiogenol C.

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Biological Activity

VUT-MK142 is a cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes, shows superior cardiomyogenic activity over cardiogenol C.
VUT-MK142 exhibits promising cardiomyogenic effects on cells of various types, upregulates the expression of ANF, as well as the expression of the cardiac key transcription factor Nkx2.5.

Physicochemical Properties

M.Wt 298.39
Formula C17H22N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N4-cyclohexyl-N6-(4-methoxyphenyl)pyrimidine-4,6-diamine

References

1. Koley M, et al. Medchemcomm. 2013 Aug 1;4(8):1189-1195.

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