Vanzacaftor | CFTR corrector | Probechem Biochemicals

Chemical Structure : Vanzacaftor

Vanzacaftor (VX-121, VX121)

Catalog No.: PC-73453Not For Human Use, Lab Use Only.

Vanzacaftor (VX-121) is a potent, selective cystic fibrosis transmembrane regulator (CFTR) corrector, with potential for treatment of cystic fibrosis.

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Biological Activity

Vanzacaftor (VX-121) is a potent, selective cystic fibrosis transmembrane regulator (CFTR) corrector, with potential for treatment of cystic fibrosis.

Physicochemical Properties

M.Wt	617.76
Formula	C32H39N7O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	13H-17,20-Methano-8,12-nitrilo-12H-pyrido[3,2-d][1,2,6,13]thiatriazacyclooctadecin-5(6H)-one, 2-[3-(2-dispiro[2.0.2.1]hept-7-ylethoxy)-1H-pyrazol-1-yl]-14,15,16,17,18,19-hexahydro-19,19-dimethyl-, 7,7-dioxide, (17S)-

References

1. Aaron Kolski-Andreaco, et al. J Clin Invest. 2024 Jul 2:e176328.

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Vanzacaftor (VX-121, VX121)

Biological Activity

Physicochemical Properties

References

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