Vav1 inhibitor AB19 | Vav1 inhibitor | Probechem Biochemicals

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Chemical Structure : Vav1 inhibitor AB19

Vav1 inhibitor AB19 (Vav1C1 inhibitor)

Catalog No.: PC-25627Not For Human Use, Lab Use Only.

Vav1 inhibitor AB19 is a small molecule inhibitor of guanine nucleotide exchange factor Vav1 atypical C1 domain (Vav1C1), effectly inhibits proliferation of Vav1-expressing cells, inhibits growth of patient-derived organoids models of pancreatic cancer.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Vav1 inhibitor AB19 is a small molecule inhibitor of guanine nucleotide exchange factor Vav1 atypical C1 domain (Vav1C1), effectly inhibits proliferation of Vav1-expressing cells, inhibits growth of patient-derived organoids models of pancreatic cancer.

Physicochemical Properties

M.Wt	538.61
Formula	C29H48BrNO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2-(2-(hydroxymethyl)-5-oxo-4-(propan-2-ylidene)tetrahydrofuran-2-yl)ethyl)-1-tetradecylpyridin-1-ium bromide salt

References

1. Bellomo A, et al. ChemMedChem. 2025 Oct 20:e202500589.

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Vav1 inhibitor AB19 (Vav1C1 inhibitor)

Biological Activity

Physicochemical Properties

References

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