Vexicitinib (SYHX1901) | JAK/SYK inhibitor

Chemical Structure : Vexicitinib

Vexicitinib (SYHX1901, SYHX-1901)

Catalog No.: PC-26362Not For Human Use, Lab Use Only.

Vexicitinib (SYHX1901) is a potent, selective dual JAK/SYK inhibitor, interrupts both the IL-23/IL-17 axis and B-cell-dependent amplification loops, shows anti-inflammatory and immunosuppressant activities.

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Biological Activity

Vexicitinib (SYHX1901) is a potent, selective dual JAK/SYK inhibitor, interrupts both the IL-23/IL-17 axis and B-cell-dependent amplification loops, shows anti-inflammatory and immunosuppressant activities.

Physicochemical Properties

M.Wt	485.56
Formula	C22H27N7O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-Pyrimidinecarboxamide, 4-(cyclopropylamino)-2-[[(4aR)-3-(cyclopropylsulfonyl)-1,2,3,4,4a,5-hexahydropyrazino[2,1-c][1,4]benzoxazin-8-yl]amino]-

References

1. Patent WO2018108084 A1.

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Vexicitinib (SYHX1901, SYHX-1901)

Biological Activity

Physicochemical Properties

References

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