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WAY-200070

Chemical Structure : WAY-200070

CAS No.: 440122-66-7

WAY-200070 (WAY200070;WAY 200070)

Catalog No.: PC-42344Not For Human Use, Lab Use Only.

WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM).

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10 mg $88 In stock
25 mg $192 In stock
50 mg $344 In stock
100 mg $616 In stock

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM); induces galanin expression within gonadotropin hormone-releasing hormone-immunoreactive neurons in the female rat brain, causes and learn the socially acquired preferenc in mice, deonstrates the anxiolytic-like and antidepressant-like effects in vivo.

Physicochemical Properties

M.Wt 306.11152
Formula C13H8BrNO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 31 mg/mL

Chemical Name/SMILES

5-Benzoxazolol, 7-bromo-2-(4-hydroxyphenyl)-

References

1. Hughes ZA, et al. Neuropharmacology. 2008 Jun;54(7):1136-42.

2. Clipperton AE, et al. Neuropsychopharmacology. 2008 Sep;33(10):2362-75.

3. Malamas MS, et al. J Med Chem. 2004 Oct 7;47(21):5021-40.

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