WDR5 WIN site inhibitor C6 TFA

You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-Histone Methyltransferase (HMTase)-WDR5 WIN site inhibitor C6 TFA

Chemical Structure : WDR5 WIN site inhibitor C6 TFA

Add to Favorites

Catalog No.: PC-22311Not For Human Use, Lab Use Only.

WDR5 inhibitor C6 TFA is a highly potent WDR5 WIN site inhibitor with Kd of 0.1 nM.

Packing	Price	Stock	Quantity
10 mg		Get quote
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

WDR5 inhibitor C6 TFA is a highly potent WDR5 WIN site inhibitor with Kd of 0.1 nM.
WDR5 inhibitor C6 inhibits cell lines and primary transformed cells carrying MLL1 rearrangements (MV4:11, IC50=3.2 uM), induces apoptosis and kills cells in a p53-dependent manner.
WDR5 inhibitor C6 rapidly displace WDR5 from chromatin and decrease the expression of associated genes, causing translational inhibition, nucleolar stress, and p53 induction.

Physicochemical Properties

M.Wt	612.41
Formula	C27H23Cl2F4N5O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, N-[(3,4-dichlorophenyl)methyl]-3-[(2,3-dihydro-2-imino-3-methyl-1H-imidazol-1-yl)methyl]-5-(6-fluoro-2-methyl-3-pyridinyl)-, 2,2,2-trifluoroacetate (1:1)

References

1. Aho ER, et al. Cell Rep. 2019 Mar 12;26(11):2916-2928.e13.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com