WEHI-518 | PfPI4KIIIB inhibitor | Probechem Biochemicals

Chemical Structure : WEHI-518

WEHI-518 (WEHI 518)

Catalog No.: PC-21094Not For Human Use, Lab Use Only.

WEHI-518 is a small molecule inhibitor of the parasite's phosphatidylinositol kinase PfPI4KIIIB, shows EC50 of 22 nM against blood-stage P. falciparum parasites.

Packing	Price	Stock	Quantity
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

WEHI-518 is a small molecule inhibitor of the parasite's phosphatidylinositol kinase PfPI4KIIIB, shows EC50 of 22 nM against blood-stage P. falciparum parasites.
WEHI-518 targets multiple stages of the asexual blood stage cell cycle, blocks invasion/early ring-stage development, does not inhibit parasite egress.
WEHI-518 (200 nM) reduces protein secretion and export in P. falciparum.

Physicochemical Properties

M.Wt	448.53
Formula	C28H24N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4-(7-(isoquinolin-6-yl)furo[3,2-b]pyridin-2-yl)phenyl)(4-methylpiperazin-1-yl)methanone

References

1. Dawson B Ling, et al. ACS Infect Dis. 2023 Sep 8;9(9):1695-1710.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

WEHI-518 (WEHI 518)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.