Chemical Structure : WHI-P131
CAS No.: 202475-60-3
Catalog No.: PC-21425Not For Human Use, Lab Use Only.
WHI-P131 (JANEX-1) is a potent and selective JAK3 inhibitor with Ki of 2.3 uM and IC50 of 78 uM, with no activity agianst JAK1 and JAK2.
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WHI-P131 (JANEX-1) is a potent and selective JAK3 inhibitor with Ki of 2.3 uM and IC50 of 78 uM, with no activity agianst JAK1 and JAK2.
M.Wt | 297.31 | |
Formula | C16H15N3O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-((6,7-Dimethoxyquinazolin-4-yl)amino)phenol |
1. Uckun FM, et al. Clin Cancer Res. 1999 Oct;5(10):2954-62.
2. Malaviya R, et al. J Biol Chem. 1999 Sep 17;274(38):27028-38.
3. Narla RK, et al. Clin Cancer Res. 1998 Oct;4(10):2463-71.
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