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WHI-P97

Chemical Structure : WHI-P97

CAS No.: 211555-05-4

WHI-P97 (WHI-P-97;WHI P97)

Catalog No.: PC-42802Not For Human Use, Lab Use Only.

WHI-P97 is a potent, specific JAK3 inhibitor with Ki of 0.6-2.3 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

WHI-P97 is a potent, specific JAK3 inhibitor with Ki of 0.6-2.3 uM.
WHI-P97 inhibits the translocation of 5-lipoxygenase (5-LO) from the nucleoplasm to the nuclear membrane and inhibits mast cell leukotriene synthesis in vitro.
WHI-P97 shows promising biological activity in mouse model of allergic asthma.

Physicochemical Properties

M.Wt 455.1007
Formula C16H13Br2N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Phenol, 2,6-dibromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]-

References

1. Malaviya R, et al. J Pharmacol Exp Ther. 2000 Dec;295(3):912-26.

2. Sudbeck EA, et al. Clin Cancer Res. 1999 Jun;5(6):1569-82.

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