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Chemical Structure : WHI-P97
CAS No.: 211555-05-4
Catalog No.: PC-42802Not For Human Use, Lab Use Only.
A potent, specific JAK3 inhibitor with Ki of 0.6-2.3 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $424 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
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A potent, specific JAK3 inhibitor with Ki of 0.6-2.3 uM; inhibits the translocation of 5-lipoxygenase (5-LO) from the nucleoplasm to the nuclear membrane and inhibits mast cell leukotriene synthesis in vitro; shows promising biological activity in mouse model of allergic asthma.
| M.Wt | 455.1007 | |
| Formula | C16H13Br2N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Phenol, 2,6-dibromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]- |
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1. Malaviya R, et al. J Pharmacol Exp Ther. 2000 Dec;295(3):912-26.
2. Sudbeck EA, et al. Clin Cancer Res. 1999 Jun;5(6):1569-82.
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