WJM228 | P.f Cyt bc1 inhibitor | Probechem Biochemicals

Chemical Structure : WJM228

WJM228 (WJM-228)

Catalog No.: PC-20289Not For Human Use, Lab Use Only.

WJM228 (WJM-228) is a potent selective inhibitor of P. falciparum cytochrome bc1, targets the Qo site of cytochrome b (cyt b), shows potent parasite activity against P. falciparum 3D7 with EC50 of 19 nM.

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Biological Activity

WJM228 (WJM-228) is a potent selective inhibitor of P. falciparum cytochrome bc1, targets the Qo site of cytochrome b (cyt b), shows potent parasite activity against P. falciparum 3D7 with EC50 of 19 nM.

Physicochemical Properties

M.Wt	370.43
Formula	C20H23FN4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-ethyl-6-fluoro-3-(3-methyl-1,2,4-oxadiazol-5-yl)-7-(4-methylpiperidin-1-yl)quinolin-4(1H)-one

References

1. William Nguyen, et al. ACS Infect Dis. 2023 Mar 10;9(3):668-691.

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WJM228 (WJM-228)

Biological Activity

Physicochemical Properties

References

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