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WWGKKYRASKLGLAR

Chemical Structure : WWGKKYRASKLGLAR

CAS No.: 130154-64-2

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WWGKKYRASKLGLAR (C3a receptor agonist, (Trp63,Trp64)-C3a (63-77))

Catalog No.: PC-21531Not For Human Use, Lab Use Only.

Peptide WWGKKYRASKLGLAR is a super agonist of complement factor C3aR, 12-15 times more active than natural C3a.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Peptide WWGKKYRASKLGLAR is a super agonist of complement factor C3aR, 12-15 times more active than natural C3a. WWGKKYRASKLGLAR selectively binds to C3aRs and induces degranulation of C3aR-transfected RBL-2H3 cells.
WWGKKYRASKLGLAR is a C-terminal analogue of C3a.

Physicochemical Properties

M.Wt 1820.1
Formula C86H134N26O18
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

L-tryptophyl-L-tryptophyl-glycyl-L-lysyl-L-lysyl-L-tyrosyl-L-arginyl-L-alanyl-L-seryl-L-lysyl-L-leucyl-glycyl-L-leucyl-L-alanyl-L-arginine

References

1. Ember JA, et al. Biochemistry. 1991 Apr 16;30(15):3603-12.

2. Proctor LM, et al. Int Immunopharmacol. 2009 Jun;9(6):800-6.

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