 
                Chemical Structure : WY-14643
CAS No.: 50892-23-4
Catalog No.: PC-45121Not For Human Use, Lab Use Only.
WY-14643 (Pirinixic acid) is a potent, selective PPARα agonist with EC50 of 0.63 uM.
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| 50 mg | $118 | In stock | |
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	WY-14643 (Pirinixic acid) is a potent, selective PPARα agonist with EC50 of 0.63 uM.
	WY-14643 displays little or no activity for PPARγ and PPARδ (EC50=32 and >100 uM, respectively).
	WY-14643 modulates cellular redox status, represses NF-kappaB signaling, and reduces inflammatory cytokine production in mice.
| M.Wt | 323.7979 | |
| Formula | C14H14ClN3O2S | |
| Appearance | Solid | |
| Storage | 
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| Solubility | DMSO: 15 mg/mL | |
| Chemical Name/SMILES | Acetic acid, 2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]- | |
1. Willson TM, et al. J Med Chem. 2000 Feb 24;43(4):527-50.
2. Forman BM, et al. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4312-7.
3. Poynter ME, et al. J Biol Chem. 1998 Dec 4;273(49):32833-41.

 
                 
                 
                 
                 
                 
                 
                 
                 
            
            
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