WYE-28 | mTOR inhibitor | Probechem Biochemicals

Chemical Structure : WYE-28

CAS No.: 1062172-60-4

Catalog No.: PC-27225Not For Human Use, Lab Use Only.

WYE-28 is a potent, selective and ATP-competitive inhibitor of mTOR with IC50 of 0.08 nM, inhibits PI3Kα with IC50 of 6 nM.

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Biological Activity

WYE-28 is a potent, selective and ATP-competitive inhibitor of mTOR with IC50 of 0.08 nM, inhibits PI3Kα with IC50 of 6 nM.

M.Wt	586.65
Formula	C30H34N8O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methyl 4-(6-(4-(3-(4-(hydroxymethyl)phenyl)ureido)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate

1. Zask A, et al. J Med Chem. 2009 Aug 27;52(16):5013-6.