Catalog No.: PC-63212Not For Human Use, Lab Use Only.
XL999 is a potent, multi-targeted receptor tyrosine kinases (RTKs) inhibitor with IC50 of 2.6, 8.2, 1.5 and 0.8 nM for VEGFR-2, FGFR-1, PDGFRβ and FLT-3, respectively.
XL999 is a potent, multi-targeted receptor tyrosine kinases (RTKs) inhibitor with IC50 of 2.6, 8.2, 1.5 and 0.8 nM for VEGFR-2, FGFR-1, PDGFRβ and FLT-3, respectively.
XL999 also potently inhibits Axl, Kit and Flt-4.
XL999 does not block c-Met but does block many other targets of XL880 and XL184, reduces the vascularity of RIP-Tag2 tumors.
