Xanthine amine congener | A1AR antagonist

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Chemical Structure : Xanthine amine congener

CAS No.: 96865-92-8

Xanthine amine congener (XAC)

Catalog No.: PC-28430Not For Human Use, Lab Use Only.

Xanthine amine congener (XAC) is a potent adenosine receptor antagonist with Ki of 0.03 nM for A1 adenosine receptor (A1AR) in bovine brain and 5.5 nM in guinea pig brain, shows marked A1 selectivity and exhibits some A2 actions.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	428.49
Formula	C21H28N6O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-Aminoethyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetamide

References

1. Morgan PF, et al. Life Sci. 1989;45(8):719-28.

2. Deckert J, et al. Neurosci Lett. 1988 Mar 31;86(2):121-6.

3. Jacobson KA, et al. J Med Chem. 1987 Aug;30(8):1529-32.

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Xanthine amine congener (XAC)

Biological Activity

Physicochemical Properties

References

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