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Y08284

Chemical Structure : Y08284

CAS No.: 2688745-47-1

Y08284 (Y 08284)

Catalog No.: PC-22485Not For Human Use, Lab Use Only.

Y08284 is a potent, selective CBP/p300 bromodomain inhibitor with IC50 of 4.21 nM (CBP bromodomain) in HTRF assays.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Y08284 is a potent, selective CBP/p300 bromodomain inhibitor with IC50 of 4.21 nM (CBP bromodomain) in HTRF assays.

Physicochemical Properties

M.Wt 476.51
Formula C26H25FN4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Acetyl-N-(3-(1-cyclopropyl-1H-pyrazol-4-yl)-2-fluoro-5-(1-hydroxyethyl)phenyl)-7-methoxyindolizine-1-carboxamide

References

1. Qiuping Xiang, et al. J Med Chem. 2022 Jan 13;65(1):785-810.

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