YCT-529 | RARα antagonist | Probechem Biochemicals

Chemical Structure : YCT-529

CAS No.: 2863670-67-9

YCT-529 (YCT529)

Catalog No.: PC-23768Not For Human Use, Lab Use Only.

YCT-529 is a potent and selective RARα antagonist with IC50 of 6.8 nM, shows no activity against RARβ and RARγ up to 30 uM.

Packing	Price	Stock
5 mg	$258	In stock
10 mg	$398	In stock
25 mg	$598	In stock
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Biological Activity

YCT-529 is a potent and selective RARα antagonist with IC50 of 6.8 nM, shows no activity against RARβ and RARγ up to 30 uM.
YCT-529 demonstrated excellent in vivo efficacy in inhibiting spermatogenesis and inducing infertility in mice, with fertility recovery following drug discontinuation.

Physicochemical Properties

M.Wt	457.50
Formula	C29H24NNaO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzoic acid, 4-[5-[2,2-dimethyl-4-(4-methylphenyl)-2H-1-benzopyran-6-yl]-1H-pyrrol-2-yl]-, sodium salt

References

1. Shi R, et al. Contraception. 2025 Jan 3:110809.

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YCT-529 (YCT529)

Biological Activity

Physicochemical Properties

References

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