YKJ-305 | Aster-C inhibitor | Probechem Biochemicals

Chemical Structure : YKJ-305

YKJ-305 (YKJ305)

Catalog No.: PC-27982Not For Human Use, Lab Use Only.

YKJ-305 is a specific, nonsteroidal small molecule inhibitor of cholesterol transfer protein Aster-C, blocks cholesterol transfer by Aster-C and inhibits fasting-induced PM-to-ER cholesterol transfer.

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Biological Activity

YKJ-305 is a specific, nonsteroidal small molecule inhibitor of cholesterol transfer protein Aster-C, blocks cholesterol transfer by Aster-C and inhibits fasting-induced PM-to-ER cholesterol transfer.

Physicochemical Properties

M.Wt	396.51
Formula	C22H24N2O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-(4-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-7-yl)-2,6-dimethylphenyl)-4-methylthiazol-5-yl)propan-2-ol

References

1. Hyunsoo Kim, et al. Proc Natl Acad Sci U S A. 2026 Sep 8;123(36):e2617638123.

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YKJ-305 (YKJ305)

Biological Activity

Physicochemical Properties

References

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