YKJ-86 | Aster inhibitor | Probechem Biochemicals

Chemical Structure : YKJ-86

YKJ-86 (YKJ86)

Catalog No.: PC-27983Not For Human Use, Lab Use Only.

YKJ-86 is a potent, pan-inhibitor of cholesterol transfer proteins Aster-A, -B, and -C, effectively blocks Aster-mediated cholesterol transport in a concentration-dependent manner and completely inhibits cholesterol transport at 10 uM in CHO-K1 cells.

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Biological Activity

YKJ-86 is a potent, pan-inhibitor of cholesterol transfer proteins Aster-A, -B, and -C, effectively blocks Aster-mediated cholesterol transport in a concentration-dependent manner and completely inhibits cholesterol transport at 10 uM in CHO-K1 cells.

Physicochemical Properties

M.Wt	294.35
Formula	C18H18N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(6-(6-methoxypyridin-3-yl)quinolin-2-yl)propan-2-ol

References

1. Hyunsoo Kim, et al. Proc Natl Acad Sci U S A. 2026 Sep 8;123(36):e2617638123.

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YKJ-86 (YKJ86)

Biological Activity

Physicochemical Properties

References

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